However, Thesereactions often require harsh conditions and was happened long reaction time and low efficiency. See comment in PubMed Commons below Molecules. Sabetpoor S, Hatamjafari F.
The bioavailability of coumarin is sessional and environment dependent, so its production is variable at large scale from the natural resources. The preliminary screening results showed that most of the compounds had moderate cytotoxic activity against HCT and MCF-7 cell ot. Get Access to Research on Chemical Intermediates. Please, wait while we are validating your browser. National Center for Biotechnology InformationU. Formerly, concentrated H 2 SO 4 was employed for the synthesis of coumarin in Pechmann reaction.On Dec 31, Fang-Fang Ye (and others) published: One-pot synthesis of coumarin derivatives. Zirconia-based catalyst for the one-pot synthesis of coumarin through However, the remarkable application of coumarin and its derivatives. Full Length Research Paper. One-pot synthesis of potential antioxidant agents, 3- carboxylate coumarin derivatives. Lijuan Han, Bing Huang.