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Purine synthesis inhibitors

Purine synthesis inhibitors synthesis of piperazine ring

Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: Cytel ; Cambridge, MA ;

Back Links pages that link to this page. For human cancer, the purine pathway may be a better target for inhibition than the pyrimidine pathway, where toxic side effects are more apparent. Powered by Wiley Online Library. Address correspondence and reprint requests to: Keywords azathioprine; leflunomide; mycophenolate mofetil.

Biochem Pharmacol. Sep 1;30(17) Effect of de novo purine synthesis inhibitors on 5-fluorouracil metabolism and cytotoxicity. Cadman E(1), Benz. is the site point for purine synthesis. GMP and AMP are inhibitors while  ‎Biosynthesis · ‎IMP · ‎Degradation. This page includes the following topics and synonyms: Purine Synthesis Inhibitor, Mycophenolate, Cellcept, Mycophenolic acid, MyFortic.

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