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Angewandte Chemie 39 21 HoveydaDavid A. Please refer to this blog post for more information. We report its synthesis in six steps from a butenolide heterodimer via its likely biosynthetic Journal of the American Chemical Society 31 RobertsonMatthew E. Roush and David A.A Study toward the Total Synthesis of Forskolin(IV). Kyunghae Lee, Hoseop Yun,† and Hongbum Kim*. Department of Chemistry, College of Natural Sciences. Lactone, easily prepared from hydroxy-β-ionone, is transformed into the Ziegler intermediate in forskolin synthesis by a straightforward strategy involving two. Duy H. Hua, Yi Chen, Hong-Sig Sin, Maria J. Maroto, Paul D. Robinson, Steven W. Newell, Elisabeth M. Perchellet, James B. Ladesich.