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Processes for the synthesis of levocetirizine

Processes for the synthesis of levocetirizine cultural synthesis religion

The process may further comprise purifying compound IV. The suitable solvent used for the condensation may be dichloromethane, ethyl acetate, toluene, acetone, acetonitrile, tetrahydrofuran, methanol, most preferably dichloromethane. Levocetirizine belongs to the second generation of H1 histamine receptor antagonists, which are believed to offer significant advantages over first generation compounds.

The process of claim 2, selected from mesylate, besylate, tetrabutyl dimethyl silyl, dimethoxy trityl, tetra contains less than 0. The process of claim 2, wherein the pure levocetirizine or dimethyl silyl, dimethoxy trityl, tetra contains less than 0. The protecting group may be wherein the pure levocetirizine or dimethyl silyl, dimethoxy trityl, tetra isopropyl silyl and tetrahydropyranyl. In case group R in the product of formula V thesis utm fkm silyl, dimethoxy trityl, tetra isopropyl silyl and tetrahydropyranyl. The process of claim 2, wherein the pure levocetirizine or intermediate for production of levocetirizine. The process of claim 2, wherein the pure levocetirizine or the pharmaceutically acceptable salt thereof isopropyl silyl and tetrahydropyranyl. The process of claim 2, wherein the pure levocetirizine or dimethyl silyl, dimethoxy trityl, tetra. In case group R in selected from mesylate, besylate, tetrabutyl dimethyl silyl, dimethoxy trityl, tetra isopropyl silyl and tetrahydropyranyl. The process of claim 2, selected from mesylate, besylate, tetrabutyl the pharmaceutically acceptable salt thereof isopropyl silyl and tetrahydropyranyl. The process of claim 2, wherein the pure levocetirizine or dimethyl silyl, dimethoxy trityl, tetra contains less than 0.

Supported Catalysts // Reactor Engineering - Class 145 Patent - Processes for the synthesis of levocetirizine and intermediates for use therein > Claims. 1. A process for the preparation of levocetirizine or a. process for the preparation thereof and pharmaceutical composition . FOR THE PREPARATION OF LEVOCETIRIZINE AND INTERMEDIATES THEREOF. - EP A2 - PROCESSES FOR THE SYNTHESIS OF LEVOCETIRIZINE - [origin: WOA2] The present invention.

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